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| R4 | Becker O'Shaughnessey d. Brandon Sutter | 6-4; 7-5 |
| R4 | Alex Fennell d. Yannik Mahlangu | 6-4; 6-2 |
| R4 | Zachary Goldberg d. Aman Manji | 7-6(5); 6-1 |
| R4 | Edgar Diaz d. Jonah Tahilan | 6-1; 6-0 |
| R4 | Sebastian Beltrame d. Goutham Sundaram | 6-2; 6-1 |
| R4 | Brendon Kempin d. Jake Norman | 6-3; 6-0 |
| R4 | Brian Page d. Charles Boyce | 6-4; 7-5 |
| R4 | Bryan Cunningham d. Thomas Nath | 6-2; 6-4 |
| R4 | Maxx Lipman d. Anthony Tsodikov | 2-6; 7-6; 6-2 |
| R4 | Josh Levine d. Henry Craig | 6-2; 6-7; 7-5 |
| R4 | Nicholas Mahlangu d. Jeremy Lynn | 7-5; 6-1 |
| R4 | Reece Acree d. Matthew Alderson | 6-4; 6-1 |
| R4 | Nathan Roper d. Tanner Berkabile | 6-3; 6-2 |
| R4 | Stephan Gonzalez d. Alec Wagner | 5-7; 6-3; 6-3 |
| R4 | Francis Tiafoe d. Brian Astrachan | 6-3; 6-3 |
| R4 | Christopher Vrabel d. Rohan Shastri | 7-5; 6-2 |
| R4 | Isaiah Brilhante d. Luis Montes | 6-0; 6-3 |
| R4 | Elliott Orkin d. Richard Pham | 7-6(7); 2-6; 6-3 |
| R4 | Benjamin Tso d. Alex Hahn | 1-6; 6-2; 6-3 |
| R4 | Augustus Ge d. Skallerud | 6-4; 6-2 |
| R4 | Daniel O'Connor d. Rosen Ilchev | 6-1; 6-0 |
| R4 | Elliott Sprecher d. Jason Jaruvang | 1-6; 7-5; 6-2 |
| R4 | James Boyd d. Andrew Yaraghi | 7-5; 7-5 |
| R4 | Thomas Pura d. Austin Kaplan | 6-1; 6-2 |
| R4 | Grant Solomon d. Mihir Kumar | 6-7(7); 6-3; 6-1 |
| R4 | Marcel Chan d. Eduardo Irizarry | 6-1; 6-7(2); 6-4 |
| R4 | Andrew (Q) Schafer d. Nicholas Hu | 6-4; 6-1 |
| R4 | Nick Wood d. Connor Farren | 6-3; 6-3 |
| R4 | Robert Turlington d. Christopher Krimbill | 3-6; 6-2; 6-2 |
| R4 | Kenneth Sabacinski d. Frederik Strabo | 6-0; 6-2 |
| R4 | Kristofer Yee d. Anthony Delcore | 6-0; 6-3 |
| R4 | McDonald d. Jordan (WC) Daigle | 4-6; 6-4; 6-1 |
| R4 | Shane Vinsant d. Jared Hiltzik | 6-7(2); 6-0; 6-2 |
| R4 | Myles Tang d. Nicolas Montoya | 6-3; 6-1 |
| R4 | Ryan Smith d. Alexander Marcinkowski | 6-1; 6-0 |
| R4 | Drew Van Orderlain d. Anton Zykov | 0-6; 6-0; 6-1 |
| R4 | Konrad Zieba d. Bayo Philips | 6-3; 6-2 |
| R4 | Maxwell Macey d. Brett Moorhead | 6-4; 6-1 |
| R4 | Quentin Monaghan d. Robbie Bellamy | Wo (inj) |
| R4 | Nicholas Naumann d. Paul Oosterbaan | 15-0 Ret (inj) |
| R4 | Harrison Adams d. Ronnie Schneider | 5-7; 6-3; 6-2 |
| R4 | Harrison O'Keefe d. Russell Einbinder | 6-2; 6-1 |
| R4 | Robert Seby d. Aren Wilson | 6-1; 6-0 |
| R4 | Alexander Van Cott d. George Goldhoff | 7-5; 6-3 |
| R4 | Jonathan Carcione d. Seth Stolar | 4-6; 6-0; 6-2 |
All Boys' 18 Singles Matches
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